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Table 2 Necrosis severity and distribution in each compound study of the training data

From: Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants

Necrosis Observation (% of hepatocytes showing necrosis)

No Sign

<5%

5%–25%

26%–50%

>50%

Sample size

Necrosis Level

0

1

2

3

4

 

1,2-dichlorobenzene

17

8

5

2

2

34

1,4-dichlorobenzene

31

4

1

0

0

36

bromobenzene

16

7

5

0

8

36

diquat

50

10

6

4

2

72

galactosamine

18

7

8

2

1

36

monocrotaline

16

11

1

0

4

32

N-nitrosomorpholine

12

17

2

1

4

36

thioacetamide

4

18

1

6

7

36

Total sample size

164

82

29

15

28

318