Table 3 Enriched KEGG pathways for switch-like genes. Enrichment scores are the number of observed genes over the number of expected genes. P-values were computed using the hypergeometric distribution.
From: Switch-like genes populate cell communication pathways and are enriched for extracellular proteins
KEGG pathway | Genes observed | Genes expected | Ration of enrichment | P-values ≤ 0.01 |
|---|---|---|---|---|
Cell Communication | 35 | 14.37 | 2.44 | 1.01E-07 |
ECM-receptor interaction | 26 | 10.69 | 2.43 | 4.57E-06 |
Focal adhesion | 42 | 24.23 | 1.73 | 1.47E-04 |
Fructose and mannose metabolism | 13 | 5.68 | 2.29 | 2.18E-03 |
Glycolysis/Gluconeogenesis | 16 | 8.19 | 1.95 | 4.61E-03 |
Long-term depression | 17 | 9.36 | 1.82 | 8.07E-03 |
Tight junction | 24 | 12.87 | 1.87 | 1.23E-03 |