Table 7 Enriched KEGG pathways for genes regulated by switch-like transcription factors. Enrichment scores are the number of observed genes over the number of expected genes. P-values were computed using the hypergeometric distribution.
From: Switch-like genes populate cell communication pathways and are enriched for extracellular proteins
KEGG pathway | Genes observed | Genes expected | Ration of enrichment | P-values ≤ 0.01 |
|---|---|---|---|---|
Antigen processing and presentation | 6 | 0.64 | 9.40 | 3.07E-05 |
Cell adhesion molecules (CAMs) | 5 | 0.97 | 5.17 | 2.54E-03 |
Cell Communication | 5 | 1.01 | 4.96 | 3.05E-03 |
Circadian rhythm | 3 | 0.19 | 16.19 | 6.45E-04 |
ECM-receptor interaction | 4 | 0.74 | 5.40 | 5.94E-03 |
Maturity onset diabetes of the young | 3 | 0.43 | 6.94 | 8.55E-03 |
PPAR signaling pathway | 5 | 0.82 | 6.07 | 1.22E-03 |
Type I diabetes mellitus | 7 | 0.56 | 12.60 | 7.63E-07 |
Type II diabetes mellitus | 4 | 0.66 | 6.07 | 3.86E-03 |