Comparative genomic profiling of Dutch clinical Bordetella pertussis isolates using DNA microarrays: Identification of genes absent from epidemic strains

Table 1 Presence of regions of difference in Dutch clinical isolates from 1993 to 2004

Region of difference Locus:	BP-number	No. of genes	Size (kb)	*ptxP1* lineage	*ptxP3* lineage
RD-3	BP0910A-BP0937	23	24.9	0% (nr strains)	0% (nr strains)
RD-5	BP1135-BP1141	7	8.6	0% (nr strains)	0% (nr strains)
RD-6	BP1158-BP1176	19	18.7	94% (nr strains)	100% (nr strains)
RD-27	BP1553	1	0.8	82% (nr strains)	100% (nr strains)
RD-10	BP1948-BP1966	18	22.7	100% (nr strains)	0% (nr strains)
RD-28	BP2122-BP2123	2	1.7	94% (nr strains)	100% (nr strains)
RD-29	BP2822-BP2839	17	16.9	94% (nr strains)	100% (nr strains)
RD-18	BP3314-BP3322	9	9.4	94% (nr strains)	92% (nr strains)
RD-1*	BP0515-BP0516	2

Regions of difference (RDs) are numbered according to Brinig et al [23]. RD-1* is part of RD-1 as was found by Brinig et al [23]. The percentage of strains harbouring the region and the number of strains analyzed are indicated. Size, refers to the size of the deletion.

ISSN: 1471-2164