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Figure 6 | BMC Genomics

Figure 6

From: Selective inhibition of yeast regulons by daunorubicin: A transcriptome-wide analysis

Figure 6

Differential expression for glycolytic genes (gly) and ribosomal protein genes (rpg) in yeast cells subjected to different treatments. Fold induction or repression values were calculated for 32 glycolytic genes and 123 ribosomal protein genes for each of the 146 stress conditions, plus the two daunorubicin treatments. The X-axis values correspond to ratios between the average of fold induction/repression for glycolitic and ribosomal protein genes for in each experiment; Y-axis indicates the probability of both sets of genes being equally affected by each treatment. Note the reverse scale of the Y-axis. Each dot represent a single stress dataset for a particular stress condition; they are grouped in several categories: Daunorubicin treatment (DNR, 1 h and 4 h, red squares), DNA damaging agents (DD, 15 conditions, blue diamonds), osmotic stress (OS, 12 conditions, green triangles), oxidative stress (Ox, 45 conditions, yellow diamond), temperature stress (T, 37 conditions, orange circle), amino acid and nitrogen starvation (N, 15 conditions, dark brown circle) and maintenance in stationary phase for long periods of time (22 conditions, red triangles). Two vertical, discontinuous lines indicate 2-fold induction or repression; note that ratio values are expressed as log2 transformants. Except for daunorubicin-treatment, all data are from references [21, 22]. Genes and conditions analysed are listed in Table 9.

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