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Figure 2 | BMC Genomics

Figure 2

From: Whole genome transcription profiling of Anaplasma phagocytophilum in human and tick host cells by tiling array analysis

Figure 2

Artemis profiles depicting the relative transcription levels of five Ap genes during infection of HL-60 (red), HMEC-1 (green), and ISE6 (blue) cells. Plots were "smoothed" by setting the sliding window average to 5. (A) Major outer membrane protein gene (omp-1A; APH_1359) transcription greater in the human cell lines compared to the tick cell line. (B) Outer membrane efflux protein (APH_1110) greater in the tick cell line compared to the human cell lines. (C) Transcription of the major surface protein 4 gene (msp4; APH_1240) only in the tick cell line. (D) Transcription of the 60 kDa chaperonin gene (groL; APH_0240) was greatest in HL-60, significantly lower in HMEC-1, and least in ISE6. (E) Equal transcription of the succinyl-CoA synthetase beta subunit gene (sucC; APH_1052) in all three cell lines.

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BMC Genomics

ISSN: 1471-2164

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