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Table 3 Differentially expressed transport associated genes in artesunate-treated cells

From: Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

Gene ID Description ART 90 min ART 3 h HS CQ
PF07_0121 NMD3 protein, putative   0,85   
PFB0435c amino acid transporter, putative   0,89   
PFE1455w sugar transporter, putative   0,92   +
PFE1150w multidrug resistance protein, Pfmdr1   1,10   
PF11_0141 UDP-galactose transporter, putative -0,86 -0,82 -  
PFC0725c formate-nitrate transporter, putative   -1,16 -  
MAL8P1.13 integral membrane protein, conserved/folate-Biopterin transporter   -1,13   
MAL13P1.206 Na+ -dependent Pi transporter, sodium-dependent phosphate transporter PfPiT   -0,90   
PF13_0252 nucleoside transporter 1 PfNT1/PfENT1   -1,32   
PFL0170w Transporter, major facilitator superfamily   -0,86 -  
PFE0410w triose or hexose phosphate/phosphate translocator, putative   -0,88 -  
PF13_0227 vacuolar ATP synthase subunit D, putative   -0,92   
PF11_0412 Vacuolar ATP synthase subunit F, putative   -0,81 -  
PF13_0130 vacuolar ATP synthase subunit G, putative   -0,82 -  
PFE0965c vacuolar ATP synthetase, subunit C putative   -0,85   
  1. Gene ID: identifier as found in PlasmoDB.
  2. Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.
  3. HS and CQ columns: over (+) or under (-) expression.
  4. Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].
  5. Genes involved in transport were selected from the pathway maps of Ginsburg [16].
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