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Table 5 Differentially expressed genes related to the mitochondrion in artesunate treated cells

From: Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

Gene ID

Description

ART 90 min

ART 3 h

HS

CQ

PF08_0054

heat shock 70 kDa protein

 

0,88

+

 

coxI

putative cytochrome oxidase I

 

-1,07

  

coI

putative cytochrome oxidase I

 

-1,15

  

PF14_0248

ubiquinol-cytochrome c reductase hinge protein, putative

 

-0,99

-

 

PFC0975c

PFCYP19, cyclophilin, peptidyl-prolyl cis-trans isomerase

 

-0,97

  
  1. Gene ID: identifier as found in PlasmoDB.
  2. Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.
  3. HS column: over (+) or under (-) expression.
  4. Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].
  5. Genes were selected based on [16].