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Table 5 Differentially expressed genes related to the mitochondrion in artesunate treated cells

From: Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

Gene ID Description ART 90 min ART 3 h HS CQ
PF08_0054 heat shock 70 kDa protein   0,88 +  
coxI putative cytochrome oxidase I   -1,07   
coI putative cytochrome oxidase I   -1,15   
PF14_0248 ubiquinol-cytochrome c reductase hinge protein, putative   -0,99 -  
PFC0975c PFCYP19, cyclophilin, peptidyl-prolyl cis-trans isomerase   -0,97   
  1. Gene ID: identifier as found in PlasmoDB.
  2. Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.
  3. HS column: over (+) or under (-) expression.
  4. Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].
  5. Genes were selected based on [16].
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BMC Genomics

ISSN: 1471-2164

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