Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

BMC Genomics

Table 6 Differentially expressed genes related to purine/pyrimidine metabolism in artesunate-treated cells

Gene ID	Description	ART 90 min	ART 3 h
PF14_0697	dihydroorotase, putative	0,96	0,93
PF13_0259	cytidine and deoxycytidylate deaminase family, putative		-1,22
PF10_0121	hypoxanthine phosphoribosyltransferase		-1,24
PF11_0282	deoxyuridine 5'-triphosphate nucleotidohydrolase, putative	-0,88	-0,95
PFE0660c	purine nucleotide phosphorylase, putative	-1,07	-1,53

Gene ID: identifier as found in PlasmoDB.
Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.
Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].
Genes were selected based on [16].

ISSN: 1471-2164