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Table 6 Differentially expressed genes related to purine/pyrimidine metabolism in artesunate-treated cells

From: Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate

Gene ID Description ART 90 min ART 3 h HS CQ
PF14_0697 dihydroorotase, putative 0,96 0,93   
PF13_0259 cytidine and deoxycytidylate deaminase family, putative   -1,22   
PF10_0121 hypoxanthine phosphoribosyltransferase   -1,24   
PF11_0282 deoxyuridine 5'-triphosphate nucleotidohydrolase, putative -0,88 -0,95   
PFE0660c purine nucleotide phosphorylase, putative -1,07 -1,53   
  1. Gene ID: identifier as found in PlasmoDB.
  2. Art columns: log ratios of gene expression under artesunate exposure at 90 minutes and 3 hours.
  3. Results were compared with transcriptome modifications induced by heat-shock (HS) [12] and chloroquine (CQ) [8].
  4. Genes were selected based on [16].