Figure 3

Relationship of receiver operating characteristic (ROC) curve and Z-score values and estimates of SFP call rates. The black line is the ROC curve, and the red line is the Z-score curve. The vertical dash line indicates false positive rate (1-specificity) of 5%, and horizon lines point to a Z-score value of 1.5 and sensitivity level (call rate) of approximately 81%, respectively. The curves were generated using data from all replicates of hybridization. SFP calls were compared with known NIAID SNP described previously (see text).