Skip to main content

Table 3 Fold changes of the mRNA levels of the apoptosis-related genes in male and female hepatocyte RXRα-deficient mouse livers.

From: Hepatocyte RXRalpha deficiency in matured and aged mice: impact on the expression of cancer-related hepatic genes in a gender-specific manner

6 month male mice (KO vs. WT) 6 month female mice (KO vs. WT)
Name Fold Change function Name Fold Change function
FKBP5 4.26 anti-apoptosis FKBP5 2.63 anti-apoptosis
USP2 3.46 anti-apoptosis USP2 2.17 anti-apoptosis
CFLAR 2.56 anti-apoptosis BCL6 2.14 anti-apoptosis
BGN 2.4 anti-apoptosis SERPINA3K 2.06 anti-apoptosis
BIK 4.41 pro-apoptosis BGN -2.12 anti-apoptosis
ACVR2B 3.55 pro-apoptosis ANP32A -2.01 pro-apoptosis
BNIP2 2.09 pro-apoptosis    
CASP8 -2.04 pro-apoptosis    
EMP2 -2.7 pro-apoptosis    
DUSP6 -4.26 pro-apoptosis    
BCL2L11 -5.61 pro-apoptosis    
24 month male mice (KO vs. WT) 24 month female mice (KO vs. WT)
Name Fold Change function Name Fold Change Function
USP2 3.97 anti-apoptosis IER3 2.23 anti-apoptosis
FKBP5 2.81 anti-apoptosis BCL6 2.08 anti-apoptosis
IER3 2.8 anti-apoptosis BIK 2.22 pro-apoptosis
DUSP1 2.3 anti-apoptosis WNK1 -2.35 pro-apoptosis
BIRC4 -3.19 anti-apoptosis DIABLO -2.87 pro-apoptosis
CASP1 2.83 pro-apoptosis    
UBE1L 2.36 pro-apoptosis    
ZBTB16 2.19 pro-apoptosis    
SOX9 -2.09 pro-apoptosis    
CASP8 -2.27 pro-apoptosis