Table 5 Fold changes of the mRNA levels of the stress-inducible genes in male and female hepatocyte RXRα-deficient mouse livers.
6 month male mice (KO vs. WT) | 6 month female mice (KO vs. WT) | ||||
|---|---|---|---|---|---|
Name | Fold Change | function | Name | Fold Change | function |
GADD45G | 3.89 | stress inducible | HSPA8 | -2.50 | stress inducible |
DDIT4 | 2.30 | stress inducible | HSPB1 | -4.66 | stress inducible |
DNAJB4 | -2.39 | stress inducible | |||
HSPA1B | -3.42 | stress inducible | |||
HSPB1 | -3.86 | stress inducible | |||
HSPA1A | -10.29 | stress inducible | |||
DNAJB1 | -11.30 | stress inducible | |||
ATF3 | -33.85 | stress inducible | |||
24 month male (KO vs. WT) | 24 month female (KO vs. WT) | ||||
Name | Fold Change | function | Name | Fold Change | function |
GADD45G | 2.86 | stress inducible | HIF1A | 2.50 | stress inducible |
DDIT4 | 2.18 | stress inducible | HIPK2 | -2.22 | stress inducible |
HSPB1 | -2.59 | stress inducible | HSPB1 | -2.62 | stress inducible |
HYOU1 | -2.75 | stress inducible | HYOU1 | -3.54 | stress inducible |