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Table 6 Fold changes of the mRNA levels of the cell growth-related genes in male and female hepatocyte RXRα-deficient mouse livers.

From: Hepatocyte RXRalpha deficiency in matured and aged mice: impact on the expression of cancer-related hepatic genes in a gender-specific manner

6 month male mice (KO vs. WT) 6 month female mice (KO vs. WT)
Name Fold Change function Name Fold Change function
LCN2 6.37 oncogene LCN2 4.57 oncogene
PIM1 4.10 oncogene GFRA1 2.15 oncogene
MAFB 4.07 oncogene PTTG1 -4 oncogene
ERBB3 2.05 oncogene PROM1 -5.61 oncogene
REL -2.34 oncogene PLAGL1 -2.09 suppressor
MDM2) -2.47 oncogene KLF6 -2.19 suppressor
JUN -2.87 oncogene WWOX -2.2 suppressor
RHOB -2.93 oncogene CAPG -2.23 suppressor
PTTG1 -2.95 oncogene KLF4 -2.32 suppressor
RHOC -3.06 oncogene GJA1 -2.91 suppressor
ROS1 -3.14 oncogene GSN -3.18 suppressor
SERTAD1 -3.7 oncogene PEG3 -5.96 suppressor
PML -3.9 oncogene TPM1 -11.95 suppressor
ETS2 -4.97 oncogene    
FOS -5.74 oncogene    
MYC -7.7 oncogene    
SOCS3 3.85 suppressor    
MAD1L1 3.73 suppressor    
TCF21 2.82 suppressor    
CEBPD 2.77 suppressor    
SSBP2 2.27 suppressor    
NDRG1 2.19 suppressor    
HMGN1 2.1 suppressor    
SLC22A18 2.08 suppressor    
AIM1 2.05 suppressor    
KSR1 2.04 suppressor    
CDKN1A -2.32 suppressor    
MBL2 -2.34 suppressor    
GSN -2.42 suppressor    
TPM1 -2.46 suppressor    
PSRC1 -2.78 suppressor    
GPX3 -2.8 suppressor    
PERP -3.42 suppressor    
MSX1 -3.5 suppressor    
MBD1 -4.15 suppressor    
BTG2 -5.26 suppressor    
KLF6 -5.67 suppressor    
EGR2 -6.03 suppressor    
EGR1 -15.88 suppressor    
24 month male mice (KO vs. WT) 24 month female mice (KO vs. WT)
Name Fold Change function Name Fold Change function
JUN 2.29 oncogene LIMK1 4.9 oncogene
PTTG1 2.25 oncogene ROS1 4.51 oncogene
PLK3 3.91 suppressor CCND1 4.44 oncogene
BLNK 2.13 suppressor APC 2.87 oncogene
GPX3 2.11 suppressor MAFB 2.57 oncogene
BEXL1 2.08 suppressor MYBL2 2.54 oncogene
WWOX -2.00 suppressor SH2B2 2.25 oncogene
PEG3 -2.2 suppressor PDGFB 2.23 oncogene
WISP1 -3.48 suppressor E2F3 2.08 oncogene
PERP -4.03 suppressor FLT4 2.02 oncogene
    MYCL1 -2.08 oncogene
    GPC1 -2.09 oncogene
    CDK5 -2.11 oncogene
    DCT -2.3 oncogene
    SH3RF1 -2.35 oncogene
    NKX2-5 -2.42 oncogene
    BANP 3.97 suppressor
    PEG3 2.91 suppressor
    IFI16 2.63 suppressor
    BLNK -2.55 suppressor
    DKK3 -4.13 suppressor
    GPR65 -6.82 suppressor