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Figure 4 | BMC Genomics

Figure 4

From: Haplotype block partitioning as a tool for dimensionality reduction in SNP association studies

Figure 4

R and B distribution. Parallel distribution of the statistics R (relative position of the block containing the right SNP) and B (number of SNPs belonging to blocks classified not worse than the true SNP) for a sample size of 500 cases and 500 controls. Four effect sizes were considered: the OR is 1.2, 1.4, 1.6 and 1.8, respectively. For each panel, the results of simulation with the allele-based single-SNP, the genotype-based single-SNP analysis, the four common methods (DprimeCI, 4Gamete, SSD and HapBlock) and the MATILDE at various cutoff thresholds are listed.

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