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Table 1 A list of the P. falciparum sequences in the four groups of protein phosphatases, with the PlasmoDB annotation available at the time of analysis.

From: The protein-phosphatome of the human malaria parasite Plasmodium falciparum

PlasmoDB ID

PlasmoDB annotation

Motifs

Key

Refs

PPP group

    

PF14_0630

protein serine/threonine phosphatase

 

A

42

PF14_0142

serine/threonine protein phosphatase, putative

 

B

45, 46

PF14_0224

PP1-like protein serine/threonine phosphatase

 

C

47, 48

PFC0595c

serine/threonine protein phosphatase, putative

 

D

49

PF10_0177

erythrocyte membrane-associated antigen

HT; SP; API

E

 

PF08_0129

protein phosphatase, putative

 

F

48

PFI1245c

Protein phosphatase-beta

 

G

52

PFI1360c

serine/threonine protein phosphatase, putative

 

H

 

MAL13P1.274

serine/threonine protein phosphatase pfPp5

 

I

55, 56

PF13_0222

RNA lariat debranching enzyme, putative

 

K

 

PFA0390w

DNA repair exonuclease, putative

 

L

 

PF14_0064

vacuolar protein sorting 29, putative

 

M

 

PF14_0036

acid phosphatase, putative

 

J

 

PF14_0660

hypothetical protein

SP; API

O

 

PFL0300c

phosphoesterase, putative

SP

P

 

PF14_0614

hypothetical protein

SP

N

 

PPM group

    

MAL13P1.44

protein phosphatase 2c-like protein, putative

 

A

 

PFL2365w

hypothetical protein, conserved

 

B

 

PF14_0523

Protein phosphatase 2C, putative

 

C

 

PFD0505c

protein phosphatase 2C

 

D

 

PFE1010w

protein phosphatase 2c, putative

 

E

 

PF11_0362

protein phosphatase, putative

 

F

 

PF11_0396

Protein phosphatase 2C

 

G

59

MAL8P1.109

Protein phosphatase 2C, putative

 

H

 

MAL8P1.108

protein phosphatase, putative

 

I

 

PF10_0093

hypothetical protein

 

J

 

PTP group

    

PF14_0524

protein phosphatase 7 homolog, putative

API

A

 

PFC0380w

dual-specificity protein phosphatase, putative

 

B

67

PF11_0139

protein tyrosine phosphatase, putative

 

C

68

PF11_0281

hypothetical protein

 

D

 

NIF group

    

PFE0795c

nif-like protein, putative

 

A

 

PF07_0110

hypothetical protein, conserved

 

B

 

PF10_0124

hypothetical protein

 

C

 

MAL13P1.275

NLI interacting factor-like phosphatase, putative

 

D

 
  1. Where necessary, an update of the PlasmoDB annotations will be submitted to the database curators. The "Motifs" column reports the targeting signals identified by the following query tools in PlasmoDB: HT, Host Targeting; SP, Signal Peptide; API, Apicoplast targeting. The "Key" column refers to the letters used to identify the sequences in the phylogenetic trees. The last column provides the references for those protein phosphatases that have been described to date in the literature. See text for details.
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BMC Genomics

ISSN: 1471-2164

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