Figure 3
Functional annotation of genes in the porcine MLN transcriptome and of genes differentially expressed (DE) between infected and non-infected pigs. A. Gene Ontology (GO) annotation of the porcine MLN transcriptome and differentially expressed genes (p < 0.01, FC > 2, q < 0.26). All 16,046 probesets which were expressed in infected and non-infected porcine MLN (gray bars) and 1,853 differentially expressed genes (white bars) were annotated using our own specific GO-slim for biological processes and molecular functions relevant to immune response. The percentage of a given GO annotation across all annotations in the differentially expressed gene list, as compared to percentage annotation of the complete transcriptome, is shown. Statistical significance is denoted with an asterisk (*p < 0.05 and ** p < 0.01). B. GO annotations for up-regulated and down-regulated genes from induced and repressed gene clusters. Analysis details and statistics are denoted as in A.