Correlation between methylation and gene responsiveness. (A) Plot of the frequency of methylated genes (according to Zhang et al. ; X-axis) within a group of genes against the number of comparisons in which that group of genes is regulated (Y-axis). The dotted line represents the regression line. B) Same as (A) except using data from Zilberman et al . C) to E). Same as (A) except with the different experimental categories defined in Figure 1A, using methylome data from Zhang et al . G) Same as (A) except the X-axis represents the frequency of genes that are the target of trimethylation on H3K27 .