|
A – Human genes with E(CG)-bearing promoters across bilaterian orthologs
|
|---|
|
ABCF1*
|
ESF1*
|
NOL11*
|
RIOK1*
|
|
ATHL1
|
GNL2*
|
NOL14*
|
RPL11*
|
|
BXDC1*
|
GRWD1*
|
NOL5_HUMAN*
|
RPL8*
|
|
BXDC5*
|
HEATR1*
|
NOL5A*
|
RRP12*
|
|
BYSL*
|
HTF9C_HUMAN*
|
NOL6*
|
RRP9*
|
|
C1orf107*
|
IMP4*
|
NOLA1*
|
RRS1*
|
|
C1orf181*
|
KAD6_HUMAN*
|
NP_060822.2*
|
SDAD1*
|
|
C6orf66
|
KIAA0020*
|
NP_079425.3
|
SRM*
|
|
CCDC86*
|
KIAA0409*
|
PAQR3
|
SURF6*
|
|
CEBPZ*
|
KLHDC4
|
PFAS
|
TIMM10
|
|
CIRH1A*
|
LYAR*
|
PNO1*
|
TRMT1*
|
|
DDX18*
|
MBIP
|
POLR1B*
|
UMPS
|
|
DDX51*
|
MEN1
|
POLR1E*
|
UTP20*
|
|
DDX52*
|
MRTO4*
|
POLRMT
|
WDR3*
|
|
DDX54*
|
MYBBP1A*
|
PRMT3
|
WDR36*
|
|
DHX37*
|
NAT10*
|
PWP1*
|
WDR75*
|
|
DPH5
|
NHP2L1*
|
PWP2*
|
WDR89
|
|
DUS3L*
|
NLE1*
|
QTRTD1*
| |
|
EBAG9
|
NM_005452*
|
RBM19*
| |
|
ELP3
|
NOL1*
|
RCL1*
| |
|
B – Human genes with E(CG)-bearing promoters across holozoan orthologs
|
|
ATIC
|
EBNA1BP2*
|
MRTO4*
|
PRMT3*
|
|
BMS1L*
|
ESF1*
|
NAT10*
|
PWP1*
|
|
BXDC1*
|
EXOSC1*
|
NHP2L1*
|
PWP2*
|
|
BXDC5*
|
FARSLB*
|
NLE*
|
SLC25A32
|
|
BYSL*
|
GTPBP9
|
NOL14*
|
SRM*
|
|
DDX4
|
KAD6_HUMAN*
|
NOP5*
|
TRMT1*
|
|
DDX54*
|
KLF15
|
PNO1*
|
VPS29
|
|
DHX37*
|
LYAR*
|
POLR3K*
| |
|
DPH5
|
MCCC2
|
PRDX4
| |
- (A) A list of all human genes with orthologous fly genes containing an E(CG) tightly linked to the core promoter in both orthologs. These genes have an E(CG) ± 600 bp and ± 80 bp from the transcriptional initiation site in the pair of human and fly orthologs, respectively. Genes with asterisks are known to be involved in ribosome biogenesis. See Additional file 1 for a more exhaustive list of genes described in this study. (B) A list of all human genes that have been evolutionarily maintained with E(CG)-bearing promoters across orthologous holozoan loci (humans, flies, cnidarians, and choanoflagellates). These genes have an E(CG) ± 600 bp from the annotated 5'-end in each genome. Missing from this list are genes that may be E(CG)-bearing in a genome but are not yet annotated by full-length transcripts. Genes with asterisks are known to be involved in ribosome biogenesis. See Additional file 1 for a more exhaustive list of genes described in this study.
