Phylogenetics analysis of expansion of the CPNE and RBM12 families. Protein sequences of the two gene families from various species were aligned using ClustalX. The aligned sequences were analyzed by MrBayes 3.1.2 for their phylogenetic distances and displayed by TreeView. The numbers shown on each branch are the posterior probabilities of the phylogenetic relationship. The circle marked the genes that shared promoters between CPNE1 and RBM12.