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Table 1 Gene pairs in human genome that share most 5' exons and promoters with little coding similarities

From: Promoter-sharing by different genes in human genome – CPNE1 and RBM12 gene pair as an example

Gene 1

Chr.

Strand

Gene 1 start *

Gene 2

Gene 2 start

Coexpression Correlation Coefficient

P-value (**)

Note

LEPOT

1

+

65658906

LEPR

65658905

-0.15

0.73 (103)

 

KLHL23

2

+

170259246

PHOSPHO2

170259220

N/A

N/A (0)

 

NAT6

3

-

50308836

HYAL3

50305265

0.33

0.16 (103)

 

TMED7

5

-

114977101

TICAM2

114942246

0.56

0.04 (105)

 

ITGA1

5

+

52119892

PELO

52119530

0.42

0.09 (95)

 

MUTED

6

-

7959212

TXNDC5

7826748

0.18

0.30 (107)

 

HIST1H2AD

6

-

26306990

HIST1H3D

26304990

0.77

<0.01 (94)

Little coding similarity

LOC552891

9

+

113433486

DNAJC25

113433483

N/A

N/A (0)

One is a fusion gene of two adjacent genes

TRIM6-TRIM34

11

+

5574461

TRIM6

5573922

N/A

N/A

One is a fusion gene of two adjacent genes

HOXC4

12

+

52696908

HOXC6

52696908

0.54

0.04 (103)

some coding similarity; HOXC5 also shares exon 1 with these two genes

ANG

14

+

20222608

RNASE4

20222211

0.77

<0.01 (104)

 

SPESP1

15

+

67009918

NOX5

67009917

0.17

0.32 (68)

 

SULT1A4

16

+

29373901

GIYD2

29373375

N/A

N/A (0)

 

SULT1A3

16

+

30113243

GIYD1

30112717

N/A

N/A (0)

Duplication of the SULT1A4/GIYD2 pair

TNFSF12-TNFSF13

17

+

7393139

TNFSF12

7393098

N/A

N/A (0)

One is a fusion gene of two adjacent genes; structure conserved in mouse

NME1

17

+

46585918

NME1-NME2

46585918

N/A

N/A (0)

One is a fusion gene of two adjacent genes

NUP62

19

-

55101893

IL4I1

55084722

-0.11

0.68 (106)

 

PEG3

19

-

62015614

ZIM2

61977731

0.34

0.14 (75)

 

ADAT3

19

+

1856416

SCAMP4

1856372

N/A

N/A (0)

 

FASTKD5

20

-

3075164

UBOX5

3036218

-0.05

0.61 (105)

Structure conserved in mouse

RBM12

20

-

33700290

CPNE1

33677379

0.47

0.06 (106)

Structure conserved in mouse

BAGE

21

-

10079666

BAGE4

10042712

N/A

N/A

 

C22orf29

22

-

18213668

GNB1L

18155937

0.06

0.45 (104)

 

ZBED1

X

-

2414454

DHRSX

2147546

0.42

0.09 (103)

 
  1. * chromosomal positions are based on NCBI human genome Build 36.3.
  2. ** refers to the number of experiments where both genes in that gene pair appeared together.