Figure 6
From: Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones
MU Japan makes mycolactone A/B not D. A) Amino acid sequence comparisons of AT domains of Module 7 of MU Agy99, MU China 98912 and MU Japan 753. Shaded residues are those known to be essential for AT substrate specificity. B) Percentage difference over 4135 bp between the three mlsB Module 7 sequences, exclusive of the AT domain of each module. C) Ion trace of m/z 765 from LC-MS/MS analysis of lipid extracts from MU Japan 753.