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Table 4 Up- or down-regulation of proteins in human iDCs in response to treatment with [BF/S+L/Ep] or cichoric acid

From: Genomics and proteomics of immune modulatory effects of a butanol fraction of echinacea purpurea in human dendritic cells

Protein Name Protein Expression Ratio: Phytocompound Treated/Control (in 0.1% DMSO, Untreated) Accession Number (SwissProt Data Base)
  [BF/S+L/Ep] (75 ug/ml) Cichoric Acid (50 ug/ml)  
  12 h 24 h 12 h 24 h  
Up-regulation in protein expression
Gelsolin 1.12 1.1 2.37 5.09 P06396
Macrophage capping protein 1.39 1.13 1.31 1.34 P40121
Actin-related protein 3 0.97 1.04 1 1.23 P61158
Coronin-1C 2.55 0.71 1.74 1.1 Q9ULV4
Beta adducing 1.1 1.49 1.34 1.69 P35612
Rho GDP-dissociation inhibitor 1 0.94 1.16 0.83 1.49 P52565
Rab GDP dissociation inhibitor beta 0.9 1.37 0.88 1.46 P50395
T-complex protein 1, epsilon subunit 1.29 1.03 1.17 1.44 P48643
Serum albumin [Precursor] 1.24 1.1 1.23 0.87 P02768
Vimentin 2.44 0.77 1.1 0.7 P08670
Protein disulfide-isomerase A3 [Precursor] 1.09 1.21 0.93 1.03 P30101
Carbonic anhydrase II 1.76 1.16 1.32 1.01 P00918
Catalase 1.14 1.21 1.28 1 P04040
Superoxide dismutase [Mn], mitochondrial 1.72 1.23 1.09 0.84 P04179
Peroxiredoxin 6 1 1.13 1.1 1.31 P30041
Biliverdin reductase A [Precursor] 1.21 1.05 1.32 1.27 P53004
Poly(rC)-binding protein 1 0.87 1 0.79 1.31 Q15365
WD-repeat protein 1 1.54 1.17 1.74 1.47 O75083
TFIIH basal transcription factor complex helicase subunit 0.88 1.06 0.86 1.36 P18074
Chloride intracellular channel protein 1 0.98 1.04 0.94 1.32 O00299
Potassium voltage-gated channel subfamily H member 5 0.89 1.07 1.14 1.68 Q8NCM2
Down-regulation in protein expression
Cofilin, non-muscle isoform 0.75 0.84 0.09 0.42 P23528
F-actin capping protein beta subunit 0.99 1.09 0.87 1.23 P47756
Actin-related protein 2/3 complex subunit 2 0.83 0.53 0.94 0.58 O15144
Profilin-1 0.84 0.76 0.6 0.51 P07737
Lamin A/C 0.81 0.69 0.45 0.76 P02545
Phosphoglycerate mutase 1 1.3 0.83 0.89 1.76 P18669
Superoxide dismutase [Cu-Zn] 0.84 0.99 0.78 1.48 P00441
Dihydrolipoyl dehydrogenase, mitochondrial [Precursor] 0.97 0.61 1.12 0.82 P09622
Galactose mutarotase 1.08 1.05 1.32 1.46 Q96C23
Delta3, 5-delta2, 4-dienoyl-CoA isomerase, mitochondrial [Precursor] 1.24 0.84 1.23 0.22 Q13011
Dihydropyrimidinase related protein-2 0.96 1.22 0.77 1.74 Q16555
26S proteasome non-ATPase regulatory subunit 13 0.94 1.32 0.95 1.42 Q9UNM6
60S acidic ribosomal protein P0 1.07 1.02 0.7 1.13 P05388
Heterogeneous nuclear ribonucleoprotein H 1 0.7 0.74 0.52 P31943