p53 induces distinct epigenetic states at its direct target promoters

BMC Genomics

Table 1 Cell line models used in this study

Name	mutated codon	mutation	amino acid change	vector	promoter	overexpression	p53 phenotype
HME1	None	none	none	none	none	none	wt parental
Ad5WT	None	none	none	Adenovirus	CMV	transient (24h)	wt accumulated
R175H	175	GCG→GCA	Arg→His	Lentivirus	CMV	stable	mt/wt accumulated
R249S	249	AGG→AGC	Arg→Ser	Lentivirus	CMV	stable	mt/wt accumulated
R273H	273	GCG→GCA	Arg→His	Lentivirus	CMV	stable	mt/wt accumulated
R280K	280	GAG→GAA	Arg→Lys	Lentivirus	CMV	stable	mt/wt accumulated

The table displays the names of samples used within this study, mutated codon position and nucleotide and amino acid change in p53 if any, vector and promoter used for p53 variant overexpression, type of overexpression and p53 phenotype of the studied cell lines.

ISSN: 1471-2164