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Table 1 Cell line models used in this study

From: p53 induces distinct epigenetic states at its direct target promoters

Name mutated codon mutation amino acid change vector promoter overexpression p53 phenotype
HME1 None none none none none none wt parental
Ad5WT None none none Adenovirus CMV transient (24h) wt accumulated
R175H 175 GCG→GCA Arg→His Lentivirus CMV stable mt/wt accumulated
R249S 249 AGG→AGC Arg→Ser Lentivirus CMV stable mt/wt accumulated
R273H 273 GCG→GCA Arg→His Lentivirus CMV stable mt/wt accumulated
R280K 280 GAG→GAA Arg→Lys Lentivirus CMV stable mt/wt accumulated
  1. The table displays the names of samples used within this study, mutated codon position and nucleotide and amino acid change in p53 if any, vector and promoter used for p53 variant overexpression, type of overexpression and p53 phenotype of the studied cell lines.