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Figure 5 | BMC Genomics

Figure 5

From: Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays

Figure 5

Chromosomal CNAs demonstrating high polysomies. (A) For chromosome 7 in C72, the LR and AR patterns are consistent with segments of CN = 5 (AAABB), 6 (AAABBB) and 7 (AAAABBB) from left to right (as partitioned by the vertical lines). The corresponding log ratios are 0.15, 0.25 and 0.35, respectively. (B) For Chr:15 in C72, the AR patterns are consistent with segments of CN = 3 (AAB), 5 (AAABB), 4 (AABB) and 3 (AAB) from left to right. The corresponding log ratios are -0.2, +0.2, 0 and -0.2, respectively. Thus, the "copy neutral" LR of 0 actually represents a CN of 4.

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BMC Genomics

ISSN: 1471-2164

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