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Table 2 Genes modulated specifically at day 2

From: Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis

Gene symbol

Gene name

FC

SEM

Hla-dmb

Major histocompatibility complex, class II, DM beta

9.13

0.47

Fbxl7_predicted

F-box and leucine-rich repeat protein 7 (predicted)

8.46

3.35

Acot12

Acyl-CoA thioesterase 12

8.19

3.28

Prl8a2

Prolactin family 8, subfamily a, member 2

7.86

2.22

Tmod1

Tropomodulin 1

6.66

0.79

Sds

Serine dehydratase

4.57

0.71

Adcyap1r1

Adenylate cyclase activating polypeptide 1 receptor 1

4.56

0.54

Sp2

Sp2 transcription factor

4.05

0.56

Vmd2l1_predicted

Vitelliform macular dystrophy 2-like protein 1 (predicted)

2.80

0.32

Crh

Corticotropin releasing hormone

2.65

0.26

Fzd4

Frizzled homolog 4 (Drosophila)

2.64

0.14

Igfbp5

Insulin-like growth factor binding protein 5

2.44

0.30

CPG2

CPG2 protein

2.32

0.08

Lss

Lanosterol synthase

2.27

0.08

Reln

Reelin

2.10

0.17

Atcay_predicted

Ataxia, cerebellar, Cayman type (caytaxin) (predicted)

2.05

0.06

Pik3c2g

Phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide

2.02

0.25

Fmo2

Flavin containing monooxygenase 2

1.97

0.22

Slc13a5

Solute carrier family 13 (sodium-dependent citrate transporter), member 5

1.90

0.11

Xlkd1_predicted

Extra cellular link domain-containing 1 (predicted)

1.81

0.15

Vps4a

Vacuolar protein sorting 4a (yeast)

1.64

0.03

C1qbp

Complement component 1, q subcomponent binding protein

1.53

0.10

Exosc2_predicted

Exosome component 2 (predicted)

1.52

0.10

Map3k6_predicted

Mitogen-activated protein kinase kinase kinase 6 (predicted)

1.51

0.09

Retnla

Resistin like alpha

0.05

0.03

Csrp2

Cysteine and glycine-rich protein 2

0.10

0.03

Dmrta1_predicted

Doublesex and mab-3 related transcription factor like family A1 (predicted)

0.11

0.00

Rax

Retina and anterior neural fold homeobox

0.13

0.04

Ide

Insulin degrading enzyme

0.14

0.02

Opcml

Opioid-binding protein/cell adhesion molecule-like

0.17

0.01

Wdr22_predicted

WD repeat domain 22 (predicted)

0.18

0.05

Nova1

Neuro-oncological ventral antigen 1

0.19

0.02

Fgf20

Fibroblast growth factor 20

0.21

0.01

Adh6

Alcohol dehydrogenase 6 (class V)

0.22

0.02

Cpg1

Candidate plasticity gene 1

0.22

0.04

Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

0.27

0.10

Gpha2

Glycoprotein hormone alpha 2

0.31

0.01

Myt1l

Myelin transcription factor 1-like

0.31

0.06

Npffr2

Neuropeptide FF receptor 2

0.33

0.07

Csn2

Casein beta

0.34

0.06

Sybl1

Synaptobrevin-like 1

0.34

0.04

Efcbp2

Neuronal calcium binding 2

0.40

0.06

Cbr3_predicted

Carbonyl reductase 3 (predicted)

0.41

0.03

Alpi

Alkaline phosphatase 1, intestinal, defined by SSR

0.41

0.04

Nrxn1

Neurexin 1

0.43

0.06

Gp2

Glycoprotein 2 (zymogen granule membrane)

0.46

0.03

Cd248_predicted

CD248 antigen, endosialin (predicted)

0.46

0.05

Ppfia3

Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3

0.59

0.02

Zfp580_predicted

Zinc finger protein 580 (predicted)

0.62

0.05

Pttg1ip

Pituitary tumour-transforming 1 interacting protein

0.65

0.05

  1. Only annotated genes with a 50% or higher fold change are included. In all cases the FC at days 5–14 was not significantly different from the control (significance at P > 0.10 to exclude transcripts not specifically upregulated or downregulated at only day 2).