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Figure 5 | BMC Genomics

Figure 5

From: Experimental analysis of oligonucleotide microarray design criteria to detect deletions by comparative genomic hybridization

Figure 5

Stretch of perfect identity in the middle of 50-mer oligonucleotides in C. elegans. Boxplots of the difference in fluorescence intensity in log2 scale between the original and perturbed 50-mer oligonucleotides. For the green boxplots, the perturbation consisted in randomizing the left and right sides of the original oligonucleotide while keeping a stretch intact in the middle. The red boxplot is associated with a randomization over the full length of the oligonucleotide. In all the cases, the perturbed oligonucleotide has the same GC content as the original oligonucleotide in an attempt to keep the melting temperature constant.

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BMC Genomics

ISSN: 1471-2164

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