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Table 5 Hepatic transcripts exhibiting differential expression between the two genotypes (F vs L)1

From: Changes induced by dietary energy intake and divergent selection for muscle fat content in rainbow trout (Oncorhynchus mykiss), assessed by transcriptome and proteome analysis of the liver

Biological function F/L ratio ANOVA SAM
GenBank Acc. N° Best-hit Swiss-Prot description LE diet HE diet P-value FDR cut off
Lipid metabolism (7.4%)
BX857103 Ceramide kinase -1.6 -2.8 < 10-3 0.1
CA376046 Nonspecific lipid-transfer protein (NLTP) 1.4 1.1 10-3 0.1
Generation of precursor metabolites and energy (18.5%)
CA366638 10-formyltetrahydrofolate dehydrogenase 1.8 1.5 < 5.10-4 0
CA342644 6-phosphogluconate dehydrogenase (6-PGDH) 2.0 1.3 0.002 0.15
BX860760 10-formyltetrahydrofolate dehydrogenase 2.0 1.9 0.003 0
CA351158 Malate dehydrogenase, cytoplasmic (MDH) 1.4 1.2 0.003 0.1
BX301878 Ubiquinol-cytochrome c reductase iron-sulfur subunit 1.6 1.4 0.006 0.1
Carbohydrate metabolism (3.7%)
BX306300 Protein phosphatase 1 regulatory subunit 3D 1.3 1.5 0.008 0.15
Amino-acid derivative metabolism (18.5%)
CA343008 Betaine-homocysteine S-methyltransferase (BHMT) 1.5 1.2 < 5.10-4 0
BX076291 Aspartate aminotransferase, mitochondrial (GOT2) 1.6 1.2 10-3 0.1
CA353510 Aspartate aminotransferase, mitochondrial (GOT2) 1.1 1.2 0.004 0.15
CA345122 4-aminobutyrate aminotransferase, mitochondrial (GABT) 1.4 1.1 0.004 0.15
CA365793 Histone H3-K9 methyltransferase 4 1.3 1.2 0.006 0.15
Protein folding/synthesis/breakdown (18.5%)
CA345680 Calpain-9 1.3 1.1 < 5.10-4 0.15
CA362332 Ubiquitin-conjugating enzyme E2 E1 (UB2E1) 1.3 1.4 < 10-3 0.1
CA351453 α-1,3-mannosyl-glycoprotein     
  2-beta-N-acetylglucosaminyltransferase 1.3 1.2 < 10-3 0.1
CA342952 Proteasome subunit beta type 7 precursor (PSB7) 1.6 1.5 0.002 0.1
BX302854 Proteasome-associated protein ECM29 homolog 1.5 1.6 0.003 0.1
Xenobiotic and oxidant (22.2%)
CA359966 UDP-glucuronosyltransferase 2A1 precursor 1.3 1.6 < 5.10-4 0
BX302905 Metal-regulatory transcription factor 1 1.2 1.4 0.003 0.1
CA387417 Stress-activated protein kinase 3 (MK12) 1.5 1.3 0.004 0.15
BX078145 7,8-dihydro-8-oxoguanine triphosphatase 1.8 1.0 0.004 0.15
BX305962 ATP-binding cassette sub-family G member 2 1.5 1.6 0.007 0.1
BX299516 Cytochrome P450 2K4 1.3 1.2 0.007 0.15
Purine and pyrimidine metabolism (15%)
BX295336 Nucleoside diphosphate kinase A -1.3 -1.1 < 5.10-4 0.15
CA381176 Equilibrative nucleoside transporter 1 -1.4 -1.4 < 10-3 0.15
Iron metabolism (3.7%)
BX909008 Transferrin receptor protein 1 -1.6 -1.4 0.005 0.15
  1. 1 According to both ANOVA (p < 0.01) and SAM (FDR < 0.15) analysis