Table 1 Hubs and clustered nodes in the luminal ER- network.
Hub | knode | Cnode | Differentially expressed neighbours | Physical interaction content | Transcriptional interaction content |
|---|---|---|---|---|---|
CCL5* | 17 | 0.000 | 0 | 35% | 65% |
TLR4* | 17 | 0.103 | 2 | 82% | 18% |
TNF* | 15 | 0.000 | 0 | 13% | 87% |
BCL2* | 14 | 0.000 | 2 | 60% | 40% |
LY96* | 14 | 0.154 | 2 | 100% | 0% |
KIT* | 13 | 0.013 | 3 | 92% | 8% |
CCL2* | 10 | 0.000 | 0 | 40% | 60% |
LYN* | 10 | 0.022 | 1 | 100% | 0% |
ERBB3* | 9 | 0.194 | 3 | 100% | 0% |
SP1 | 9 | 0.000 | 8 | 0% | 100% |
FAS* | 8 | 0.000 | 0 | 25% | 75% |
MUC1* | 8 | 0.143 | 1 | 100% | 0% |
GRB2 | 7 | 0.000 | 6 | 100% | 0% |
UBQLN4 | 7 | 0.000 | 6 | 100% | 0% |
CD82* | 6 | 0.133 | 1 | 100% | 0% |
KRT18* | 6 | 0.067 | 1 | 83% | 17% |
NFKB1 | 6 | 0.000 | 5 | 0% | 100% |
ATXN1 | 5 | 0.000 | 4 | 100% | 0% |
CD14* | 5 | 0.100 | 2 | 40% | 60% |
CREB1 | 5 | 0.000 | 4 | 20% | 80% |
EGFR | 5 | 0.300 | 4 | 100% | 0% |
ERBB2 | 5 | 0.300 | 4 | 100% | 0% |
MAPK1 | 5 | 0.000 | 4 | 100% | 0% |
PIK3R1 | 5 | 0.000 | 4 | 100% | 0% |
RPS6KA5* | 5 | 0.000 | 0 | 100% | 0% |
SPI1 | 5 | 0.000 | 4 | 0% | 100% |