CG identifier | Gene name synonymsa | Inferred functiona | Inferred biological processa | Supporting evidence |
---|---|---|---|---|
CG18624 | Â | Putative NADH dehydrogenase | Mitochondrial electron transport | Pfam domain; GO term designation |
CG12664 | ld14, fend b | Unknown | Neuromuscular development | [61, 62] |
CG12788/CG17767c | Tim9bb (uORF) | Mitochondrial inner membrane translocase subunit (uORF) | Transport across mitochondrial inner membrane (uORF) | Interpro domain |
CG33713/CG33714c | Â | Acyl-CoA binding (mORF) RNA binding (uORF) | Unknown | Interpro domain |
CG3240 | Rad1 b | Putative 3'->5' exonuclease activity | DNA repair | [63, 64] |
CG9960/CG9958c | snapin (uORF) | Putative methyltransferase (mORF) Putative Biogenesis of Lysosome-related Organelles Complex-1-like (BLOC-1-like) subunit (uORF) | Biogenesis of lysosome-related organelles (eg. melanosomes and platelet dense granules; uORF) | [65] (uORF) Interpro domain (mORF) |
CG31917 | TFB5 (uORF) | Putative TFIIH subunit (uORF) | Transcription and DNA repair (uORF) | [66, 67]; Interpro domain |
CG31919/CG33995c | Â | Ankyrin repeat, protein-protein interactions | Target of transcription factor Glial cells missing (Gcm), involved in neuronal development and function | Interpro domain; [68] |
CG18042 | lmg b | Putative component of Anaphase Promoting Complex (uORF) | Mitosis; Neural development (unclear whether it is the uORF, mORF or both) | [69, 70]; Flybase personal communication FBrf0125046; [71]; NCBI Conserved Domain Search |
CG7400 | Fatp b | Putative very-long-chain fatty acyl-CoA synthetase | Fatty acid metabolism | [72] |
CG16974 | Member of LIG superfamilyb | Leucine-rich repeat and Immunoglobulin domain-containing protein | Unknown | [73, 74] |
CG4824 | BicC b | RNA binding protein | Anterior-Posterior patterning | [75–77] |
CG17325 | Â | Unknown | Unknown | Â |
CG10570 | Â | Unknown | Unknown | Â |
CG11508 | DmSNAP50, DmPBP49 b | Subunit of an snRNA transcriptional activator protein | Transcription of splicing factors | [78] |
CG8026 | Â | Mitochondrial carrier protein | Mitochondrial folate transport | [37, 38] |
CG17759b (uORF2) | Galpha49B, Gqα b | G-protein subunit | Photoreceptor signal transduction; Axonal guidance | [79–81] |
CG33671/CG33672c | Â | Mevalonate kinase (mORF); BolA-like protein, putative nucleic acid binding protein (uORF) | Isoprenoid production (mORF) | [82, 83] |
CG6191 | Â | Unknown | Unknown | Â |
CG30100 | Â | Translation release factor | Translation termination | GO term designation |
CG17725 | Pepck b | Putative phosphoenolpyruvate carboxykinase | Gluconeogenesis; Starvation; Glyceroneogenesis | [84–86] |
CG5469 | Gint3 b | Ubiquitin regulatory X domain (UBX), putative RNA binding | Unknown | [87]; FBrf0189302 |
CG33786/CG33785c | Â | Unknown | Translation (mORF) Transcription (uORF) | Interpro domain |
CG9865b (uORF1) | Â | Putative mannosyl transferase | Unknown | Interpro domain |
CG9865b (uORF2) | Â | Putative mannosyl transferase | Unknown | Interpro domain |
CG9865b (uORF3) | Â | Putative mannosyl transferase | Unknown | Interpro domain |
CG9878 | Tim10 b | Putative inner mitochondrial membrane translocase | Protein transport across mitochondrial membrane | [88] |
CG30290 | Â | Putative flavoprotein enzyme | Unknown | Interpro domain |
CG12016 | Â | Unknown | Unknown | Â |
CG32573 | Â | Unknown | Unkown | Â |
CG11989 | Ard1 b | Putative N-Acetyltransferase catalytic subunit | Unknown | [89]; Interpro domain |
CG7869 | SuUR b | DNA binding | Endoreplication | [90, 91] |
CG7628 | Â | Phosphate transporter | Phosphate transport | Interpro domain |
CG9666 | Â | Putative methyltransferase | Unknown | Interpro domain |
CG2128 | Hdac3 b | Histone deacetylase | Wing development; Chromatin remodeling | [92, 93] |
CG9288 | Â | Pyruvate kinase | Unknown | Interpro domain |
CG9924 | Rdx b | Unknown | Regulator of Hedgehog response (growth and development) | [94, 95] |
CG31241 | DTL b | Putative RNA methylase | Late larval development | [24]; Interpro domain |
CG31178 | Â | Unknown | Unknown | Â |
CG7071/CG34131c | Â | Unknown | Unknown | Â |
CG10238 | MOCS2 b | Molybdopterin synthase large subunit (mORF) and small subunit (uORF) | Production of molybdopterin; Implicated in mammalian neurological damage | [23, 96] |
CG5116 | Â | Putative GTP-binding protein | Unknown | Interpro domain |
CG14550 | Â | Putative phosphatidylinositol N-acetylglucosaminyltransferase subunit P (mORF); Pcc1-like transcription factor (uORF) | Unknown | Interpro domains |
CG7950 | Â | Putative tRNA processing enzyme subunit (uORF) | tRNA processing (uORF) | Interpro domain |