Comparative kinomics of human and chimpanzee reveal unique kinship and functional diversity generated by new domain combinations

Table 3 Most frequent accessory domains found in the chimpanzee and human PPKs.

	Chimpanzee		Human
Domain, short domain id, PFAM id	Freq^a	Nb_prot^b	Freq	Nb_prot
Immunoglobulin I-set, I-set, PF07679	96	34	106	37
Fibronectin type 3, Fn3, PF00041	67	27	69	28
Ankytin repeat, Ank, PF00023	51	6	50	6
Immunoglobulin, Ig, PF00047	46	29	47	30
Src homology 2, SH2, PF00017	32	29	37	34
Phorbol esters/diacylglycerol binding domain, C1_1, PF00130	30	22	36	26

Only domains seen more than 30 times are listed. ^a: domain frequency in the given kinome, ^b: number of proteins containing this domain.

ISSN: 1471-2164