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Table 2 Potentially functionally significant amino acid variants

From: Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus

Gene Amino Acid MM MS HS RN GG BT CF XT MD TR SIFT
Slc26a3 His38Asn His Asn His His His His His His His His 0.13
Dus4L Cys104Tyr Cys Tyr Cys Cys Asn Cys Cys Ser Cys Ala 0.18
Cog5 Ser769Ala Ser Ala Ser Ser Ser Ser Ser NH Ser Ser 0.09
1110049B09Rik Pro691Ala Pro Pro/Ala Pro Lys Pro Pro Pro Pro Pro NH 0.11
F730043M19Rik Asn133Ile Asn Ile/Asn NH NH NH NH NH NH NH NH 0.00
4930504H06Rik Met64Val Met Val Met Met NH Met Met NH Met Phe 0.13
Ahr Leu348Phe Leu Phe Leu Leu Leu Leu Leu Leu Leu Leu 0.01
  Ser790Gly Ser Gly Asn Ser Asp Asn Asn Asn His NH 0.15
Ankmy2 Ile369Thr Ile Thr Ile Thr Leu Leu Leu Glu Leu NH 0.03
Sostdc1 Cys15Ser Cys Ser Cys Cys Cys Cys Cys Cys Cys Cys 0.00
Ifrd1 Leu449Phe Leu Phe Phe NH Phe Phe Phe Leu Phe Phe 0.00
EG629820 Gly47Ser Ser Ser/Gly NH NH NH NH NH NH NH NH 0.00
  Gly70Ser Gly Ser/Gly NH NH NH NH NH NH NH NH 0.00
  Asn72Tyr Asn Tyr/Asn NH NH NH NH NH NH NH NH 0.00
Zfp277 Val21Phe Val Val/Phe Ser NH NH Asp Asp NH NH NH 0.08
  Gln43His Gln Gln/His Gln NH Gln Gln Gln Gln Gln Gln 0.15
Immp2L Ala8Val Ala Val Val Val Gly Val Val NH Gly Gly 0.15
Lrrn3 Ala69Gln Ala Ala/Gln Ala Ala Ala Ala Ala NH Ala Leu 0.08
  Ala671Val Ala Ala/Val Ala Ala Ser Ala Thr NH Ala NH 0.15
Stxbp6 Ile23Val Ile Val Val Val Val NH Val Val Val Val 0.12
  1. Bold indicates significant SIFT scores. No known homology (NH), Mus musculus (MM), Mus spretus (MS), Homo sapiens (HS), Rattus norvegicus (RN), Gallus gallus (GG), Bos Taurus (BT), Canis familiaris (CF), Xenopus tropicalis (XP), Monodelphis domestica (MD), and Takifugu rubripes (TR). Sift scores in bold are predicted to be non-tolerated changes.
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