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Table 5 Evolutionary conservation of variants seen between M. Spretus strains

From: Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus

Gene Variant HS RN GG BT CF XT MD SIFT
Lamb1-1 Gly1334Asn Asp Asp NH NH Asp NH NH 0.47
Cog5 Asp538Glu Asp Asp Asp Asp Asp NH Glu 1
  Asp742Glu Ser NH Asn Ser Ser NH Arg 0.92
1110049B09rik Pro691Ala Pro Lys Pro Pro Pro Pro Pro 0.11
F730043M19Rik Ser115Leu NH NH NH NH NH NH NH 0.21
  Asn133Ile NH NH NH NH NH NH NH 0.00
Twistnb Asn322Asp Glu Asn Glu Glu Glu Asn Leu 0.39
Hdac9 Ile265Met Ile Ile Leu Thr Ile Leu Leu 0.33
  Gly749Ser Gly Gly Gly Gly NH NH Ala 1.00
  Ala994Val Val Ala Ile Val NH NH Ile 1.00
Ahr Asn533Ser Ser Ser Ser Asn Ser Asn Leu 1.00
  Asn544Asp Asp Asp Asn Phe Asp Asp Gly 0.66
EG629820 Gly47Ser NH NH NH NH NH NH NH 0.00
  Gly70Ser NH NH NH NH NH NH NH 0.00
  Asn72Tyr NH NH NH NH NH NH NH 0.00
Zfp277 Gln21Phe Gln NH Gln Gln Gln Gln NH 0.15
  Val434His Ser NH NH Asn Arg NH Asp 0.08
Lrrn3 Ala69Gln Ala Ala Ala Ala Ala NH Gln 0.08
  Leu670Val Phe Leu Ile Phe Phe NH Ile 0.23
  Ala671Val Ala Ala Ser Ala Thr NH Phe 0.15
DnaJB9 Phe10Leu Phe Phe Phe Phe Phe Phe Ala 1.00
NrCam Gln152Arg Gln Arg Arg Arg Arg Gln Phe 0.49
  1. Bold indicates significant SIFT scores. No known homology (NH), No sift score generated (NSS) M. musculus (MM) Homo sapiens (HS), Rattus norvegicus (RN), Gallus gallus (GG), Bos Taurus (BT), Canis familiaris (CF), Xenopus tropicalis (XP), and Monodelphis domestica (MD).