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Table 1 Tumor suppressor genes in human and mouse

From: Prediction-based approaches to characterize bidirectional promoters in the mammalian genome

BOC gene

Bidirectional partner

Annotation of partner

Distance between TSSs

CpG island at TSSs

BARD1 (Human)

DA865307

mRNA, EST

518

Across/First exon of both

BARD1 (Mouse)

AK007117

mRNA

-425

Across/First exon of both

BRCA1 (Human)

NBR2

KG, mRNA, EST

81

Inside NBR2

BRCA1 (Mouse)

NBR1

KG, mRNA, EST

259

No CpG

BRCA2 (Human)

DR731263

EST

955

Overlaps First Exon of BRCA2

BRCA2 (Mouse)

CO801197

EST

2505

Overlaps First Exon of BRCA2

CHK2 (Human)

HSC20

KG, EST

32

Overlaps First Exon of both

CHK2 (Mouse)

AW049829

KG, mRNA, EST

276

Across/First exon of both

ERBB2 (Human)

Perld1

KG, mRNA, EST

60

Overlaps First Exon of both

ERBB2 (Mouse)

Perld1

KG, mRNA, EST

11,994

CpG at first exon of both

P53 (Human)

AK001247

KG, mRNA, EST

491

Overlaps First Exon of P53 Partner

P53 (Mouse)

WDR79

KG, mRNA, EST

657

Across/First exon of both

FANCA (Human)

Spisre2

mRNA, EST

1,533

Overlaps First Exon of both

FANCA (Mouse)

Spisre2

KG, mRNA, EST

14,137

CpG at first exon of both

FANCB (Human)

MOSPD2

KG, mRNA, EST

372

Across/First exon of both

FANCB (Mouse)

AK035985

KG, mRNA, EST

257

No CpG

FANCD2 (Human)

BC043599

KG, mRNA, EST

64

Across/First exon of both

FANCD2 (Mouse)

Tmem111

KG, mRNA, EST

47

Across/First exon of both

FANCF (Human)

GAS2

mRNA, EST

-199

Across/First exon of both

FANCF (Mouse)

AK014509

mRNA

1,966

Overlaps First Exon of FANCF partner