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Figure 2 | BMC Genomics

Figure 2

From: Short Linear Motifs recognized by SH2, SH3 and Ser/Thr Kinase domains are conserved in disordered protein regions

Figure 2

Conservation score and SH2 selectivity values of Tyr-SLiMs in disordered and ordered protein regions in 11 most studied RTKs. (A) SH2 binding Tyr-SLiMs are significantly more conserved than those that do not bind to SH2 domains in both order and disorder groups (both p < 0.001, Mann-Whitney test). (B) Percentage of SLiMs that reported to interact with SH2 domains.

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