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Table 2 Top-ten DE genes after LPS or PMA-Ionomycin stimulation, T4 and T24

From: Genome-wide immunity studies in the rabbit: transcriptome variations in peripheral blood mononuclear cells after in vitro stimulation by LPS or PMA-Ionomycin

   T4 T24
   Gene symbol FC 1 Adj.P.Val Gene symbol FC 1 Adj.P.Val
LPS Up - regulation CXCL11 3.20 4.11E-02 F3 50.10 2.91E-04
LMTK2 2.69 1.45E-02 IL6 26.96 2.09E-04
RETN 2.35 3.11E-02 SAA1 26.27 9.37E-04
IL12A 2.29 3.85E-02 IL1B 18.12 2.96E-03
HENMT1 2.28 4.87E-02 IL10 17.61 6.48E-04
UBE2D2 2.11 4.44E-02 IL36G 17.11 9.49E-05
EVA1B 2.10 4.96E-02 S100A12 15.74 4.69E-02
SPTBN4 1.95 3.85E-02 TNIP3 11.33 1.57E-03
PKHD1L1 1.56 4.11E-02 HBEGF 9.67 2.49E-05
NOS2 1.47 4.72E-02 CCL4 9.10 4.12E-02
Down - regulation CTSE2 −3.38 3.11E-02 PALLD −9.64 2.33E-05
CHI3L1 −2.90 3.44E-02 MLANA −8.12 4.55E-07
SAMHD1 −2.90 3.85E-02 DEFB1 −6.9 3.05E-03
CLEC4D −2.89 3.28E-02 ATP6V0D2 −6.59 4.25E-06
ALDOA −2.83 1.92E-02 CLEC7A −6.23 6.12E-06
TKT −2.82 2.25E-02 SLAMF7 −6.09 1.86E-04
ATP6V0B −2.79 1.25E-02 ASPA −5.15 3.65E-04
PGAM1 −2.78 3.84E-02 CTBS −4.98 3.24E-04
COMT −2.78 6.21E-03 BPI −4.92 5.73E-03
FHOD1 −2.78 1.63E-02 MPEG1 −4.46 1.65E-03
PMA - Ionomycin Up - regulation CSF23 227.98 5.78E-12 CSF23 57.58 1.99E-10
IL133 144.98 4.40E-18 BCO24 51.95 1.07E-13
IL43 105.19 7.22E-12 CD704 34.74 2.65E-11
NFKBID3 61.72 3.67E-14 RGCC3 31.77 4.15E-12
TBX213 57.61 1.40E-14 SPRY13 29.99 6.87E-17
SPRY13 53.40 2.41E-18 ZBTB323 29.31 1.26E-11
IL23 40.01 9.61E-18 CCNB14 21.20 3.78E-11
RGCC3 33.61 5.83E-12 I23 20.36 1.07E-15
MMP33 33.33 3.67E-14 LAG33 19.70 7.93E-12
IL103 33.33 2.28E-06 NCAPG4 18.80 2.07E-12
Down - regulation FAM26F −48.36 3.10E-11 S100A83 −146.61 4.01E-08
RBP43 −32.07 2.32E-08 RBP43 −67.53 4.27E-10
TRAF3IP33 −21.39 6.70E-11 MGP −58.62 4.98E-13
IL163 −18.62 4.17E-10 DEFB1 −51.43 6.61E-09
LTB3 −18.29 1.24E-07 S100A123 −42.78 1.89E-04
TM4SF53 −16.79 1.27E-09 ACTA2 −40.95 1.71E-12
CD79B −16.07 1.37E-06 LTB3 −33.98 2.45E-09
MYRFL3 −15.90 3.67E-14 PID13 −33.27 7.21E-09
TLR10 −15.62 7.66E-11 TM4SF53 −32.16 2.12E-11
TNFAIP8L23 −14.95 6.25E-05 CYBB3 −31.07 8.87E-12
  1. 1FC: fold change.
  2. 2Genes found to be DE in the same direction (either down- or up-regulated compared to mock-stimulation) at both T4 and T24 post-stimulation by LPS.
  3. 3Genes found to be DE in the same direction (either down- or up-regulated compared to mock-stimulation) at both T4 and T24 post-stimulation by PMA-Ionomycin.
  4. 4Genes that were down-regulated at T4 in contrast to T24.