miRNA-miRNA synergistic network. This network incorporates the miRNA relations that ranked in the upper quartile (639 edges) of the Borda voting scheme. Blue colored nodes represent miRNAs involved in mouse consensus modules. Edges with larger width highlight the relations included in consensus modules. Red colored nodes represent age-dependent miRNAs as estimated by linear regression analysis. Red colored miRNAs with blue border are both age-dependent and participate in consensus modules. Nodes with orange colored border represent miRNAs associated to human cardiac pathophysiology as reported in miR2Disease database. Purple edges highlight the 10 top scoring miRNA relations.