Co-expression of all genes with
gene in CQR and CQS parasites. (A) Correlation between the levels of each transcript in the genome to that of pfcrt, determined separately for CQS (x-axis) and CQR (y-axis) parasites. Grey region indicates genes whose correlation to pfcrt passed the threshold of FDR ≤ 0.20. (B) Average correlation between pfcrt and each transcript in 100 pairs of randomly sampled subsets of CQS (x-axis) and CQR (y-axis) parasites. Each subset of CQR or CQS parasites consists of transcriptional data from 8 parasite clones. (C) Average correlation between the transcript level of each gene to that of pfcrt in 100 pairs of randomly sampled subsets of CQS parasites. (D) Comparison of average pfcrt correlations in 100 pairs of randomly sampled subsets of CQR parasites. Like in (B), each randomly sampled subset of parasites consists of 8 parasites.