Figure 11

Overlapping Alzheimer-related protein association network of AD-iPS5 neurons and of AD-iPS26B neurons. Protein association network of genes down-regulated in both AD-iPS5 neurons vs. H9 neurons and in AD-iPS26B neurons vs. H9 neurons comparisons of one neuronal differentiation. Protein interaction network retrieved from STRING v9 using genes from the Alzheimer disease pathway down-regulated in AD-iPS5 vs. H9 neurons and in AD-iPS26B vs. H9 neurons experiments. The network circles represent proteins. The lines between the circles show the functional association. Co-expression evidence: black, database evidence: light blue, textmining evidence: yellow, experimental evidence: purple, co-occurrence evidence: blue, neighborhood evidence: green, fusion evidence: red.