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Figure 3 | BMC Genomics

Figure 3

From: Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks

Figure 3

Neuronal differentiation of AD-iPSCs. Induction of neuronal cells by simultaneous treatment with inhibitors of transforming growth factor (TGF)-β receptor and MEK1/2 for 4 weeks. Neuronal cells derived from AD-iPSCs (a): AD-iPS5 neurons and (b): AD-iPS26B neurons showed the expression of neuronal markers, including PAX6, NESTIN and -β-TUBULIN III in a similar fashion as neuronal cells derived from the hESC line (c): H9. The neuronal differentiation was carried out once per AD-iPS cell line or H9 cell line. Scale bar, 100 μm.

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BMC Genomics

ISSN: 1471-2164

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