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Table 1 The frequency of the L1014F and N1575Y mutations in An . coluzzii tested in deltamethrin resistance bioassays

From: The recent escalation in strength of pyrethroid resistance in Anopheles coluzzi in West Africa is linked to increased expression of multiple gene families

Period Status L F n (alleles) (f) L1014F 95% CI N Y n (alleles) (f) N1575Y 95% CI
VK7            
Jul-11 Control 22 102 124 0.823 0.744-0.886 80 44 124 0.355 0.276-0.442
Dead 23 97 120 0.808 0.728-0.870 92 34 126 0.270 0.200-0.354
Survivors 19 95 114 0.833 0.754-0.892 80 30 110 0.273 0.198-0.363
Oct-11 Control 27 163 190 0.858 0.801-0.901 134 56 190 0.295 0.234-0.363
Dead 42 194 236 0.822 0.768-0.866 174 60 234 0.256 0.205-0.316
Survivors 15 133 148 0.899* 0.839-0.939 91 55 146 0.377* 0.302-0.458
Jun-12 Control 25 183 208 0.880 0.828-0.918 151 55 206 0.267 0.211-0.331
Dead 9 45 54 0.833 0.710-0.912 42 12 54 0.222 0.131-0.351
Survivors 14 132 146 0.904 0.844-0.943 90 56 146 0.384* 0.309-0.465
Jul-13 Control 16 126 142 0.887 0.823-0.934 109 33 142 0.232 0.166-0.311
Tengrela            
Jul-12 Control 14 100 114 0.877 0.803-0.931 87 27 114 0.237 0.162-0.326
Dead 18 80 98 0.816 0.725-0.887 66 32 98 0.327 0.235-0.429
Survivors 11 81 92 0.880 0.796-0.939 66 26 92 0.283 0.194-0.386
Jul-13 Control 24 124 148 0.838 0.768-0.893 109 39 148 0.264 0.194-0.342
  1. Allele frequencies with 95% CI of 1014F and 1575Y kdr alleles in An. coluzzi from Tengrela and VK7. VK7 samples are stratified according to deltamethrin exposure (unexposed control samples and mosquitoes that died or survived exposure to an approximate LT50). In Tengrela the exposure time was one hour. Sample sets where allele frequency is significantly associated with insecticide survival (P <0.05) are marked by *.
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