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Table 2 Whole-genome comparisons between predictions and current Sc. pombe and S. cerevisiae annotations

From: CodingQuarry: highly accurate hidden Markov model gene prediction in fungal genomes using RNA-seq transcripts

 

Nucleotide

Exon

Intron

Gene

 

Sn

Sp

Sn

Sp

Sn

Sp

Sn

Sp

Sc. pombe (all 5124 genes)

CodingQuarry

98.6

98.9

90.3

89.4

92.6

95.2

87.5

83.0

AUGUSTUS

98.0

99.3

89.0

90.6

94.2

92.7

83.1

87.7

TransDecoder

93.4

99.2

80.8

85.4

85.3

96.6

76.3

72.5

S. cerevisiae (all 6575 genes)

CodingQuarry

97.2

99.5

76.1

87.2

64.4

65.8

76.6

88.3

AUGUSTUS

95.4

99.6

71.1

88.9

60.5

69.3

71.5

89.8

TransDecoder

87.8

99.7

67.1

75.0

60.5

70.1

67.8

68.0

  1. Sensitivity (Sn) is the proportion of a given feature (nucleotides/exons/introns/genes) in the annotation that are correctly predicted. Specificity (Sp) is the proportion of features in the predicted set that are correct. Sensitivity and specificity calculations for nucleotides are made on nucleotides within coding regions. Further descriptions of these measures are given in the Implementation subsection titled “Quantifying prediction results” The highest scores in each column for Sc. pombe and S. cerevisiae are shown in boldface.