Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria

BMC Genomics

Table 2 Iron system in the studied strains, comprising in silico and phenotypical results

Strain	Species	Response in AHL monitor		AntiSMASH	Siderophore (CAS)	AntiSMASH		Fur
Strain	Species	Cv	At	HSL	Siderophore (CAS)	Siderophore	NRPS	Fur
S2753	Photobacterium halotolerans	-	-	0	+	1	4	1
S2052	Vibrio coralliilyticus	(+)	-	0	-	1**	4***	1
S2043	Vibrio coralliilyticus	(+)	-	0	(+)	1**	4***	1
S2604	Vibrio nigripulchritudo	-	-	0	-	0	4***	1
S2394	Vibrio neptunius	-	-	0	(+)	1	3***	1
S2757	Vibrio sp.	+	+	0	+	1**	0	1
S2040	Pseudoalteromonas piscicida	-	-	0	+	0	11***	1
S2724	Pseudoalteromonas piscicida	-	-	0	+	0	5***	1
S816	Pseudoalteromonas agarivorans	-	-	0	+	1	0	1
S3258	Pseudoalteromonas ruthenica	-	-	0	+	1	0	1
S3137	Pseudoalteromonas ruthenica	-	-	0	-	1	0	1
S4054	Pseudoaltermonas luteoviolacea	+	+	1	(+)	0	11***	1
S2471	Pseudoalteromonas rubra	-	-	0	(+)	0	9***	1
S2151	Halomonas sp.	-	-	0	(+)	1	0	1
S3726	Marinomonas sp.	-	-	0	+	0	3***	1
S2292	Spongiobacter sp.	-	-	0	-	0	1	1
S4079	Loktanella sp.	-	-	1	(+)	0	1***	1
S4493	Paracoccus sp.	+	+	4	-	0	2	0
S1942	Ruegeria mobilis	-	-	2	(+)	0	1***	1
F1926	Ruegeria mobilis	-	-	2	(+)	0	1***	1
DSM17395	Phaeobacter inhibens	-	+	2	+	1*	1	1

Cv: Chromobacterium violaceum, At: Agrobacterium tumefaciens, HSL: homoserine lactone, CAS: chrome-azurol-S, + : strong bioactivity, (+) : weak bioactivity, − : no bioactivity detected under the tested conditions, NRPS: including single NRPS clusters and NRPS fusion clusters (e.g. NRPS-bacteriocin, NRPS-ectoine). *Located on a plasmid; **Cluster identified as a siderophore – ectoine cluster; ***At least one NRPS is in proximity to siderophore-associated genes (tonB-dependent receptor etc.).

ISSN: 1471-2164