Figure 6From: Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals Adaptation of SIMPLE to detect L1 3’ ends. (A) CLC Genomics Workbench window view of a representative fixed human specific L1 element (L1Hs) detected by 3’-SIMPLE. L1Hs represents a known human specific L1 element on chromosome 1. Small red lines at bottom are reverse 3’-SIMPLE reads, reading into the3 end of the L1Hs element. (B) Frequency distribution of the number of reference L1Hs elements detected by 3’-SIMPLE versus the number of independent 3’-SIMPLE hits detected for that element. On average, a reference L1Hs element was assayed by seven independent 3’-SIMPLE reads, with the vast majority of reference L1Hs elements assayed by at least two independent reads.Back to article page