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Table 3 Antibiotic and heavy metal resistance genes identified within ETEC O157

From: Comparative genomic analysis of a multiple antimicrobial resistant enterotoxigenic E. coli O157 lineage from Australian pigs

Resistance gene/Operon O157 SvETEC O157:K88 734/3 Phenotypic function/Resistance Resistance observed
intI1 + + Class 1 Integron Integrase  
intI2 + + Class 2 Integron Integrase  
bla TEM + + Ampicillin +
ampC + + Cephalosporins O157:K88 734/3 only
gyrA + + Quinolones +
aphA1 + + Aminoglycosides +
APH(4)-IA +   Hygromycin B O157 SvETEC only
strAB + + Streptomycin +
aadA + + Streptomycin and Spectinomycin +
dfrA + + Trimethoprim +
aacC +   Apramycin O157 SvETEC only
sul1 + + Sulphonamides +
sul2 + + Sulphonamides +
sul3 +   Sulphonamides +
macAB + + Macrolides  
tet operon + + Tetracycline +
cmlA +   Chloramphenicol O157 SvETEC only
emr operon + + RND Efflux Pump  
gadX + + Acid Resistance Regulator  
mdt operon + + RND Efflux Pump  
cus operon + + Heavy Metals  
mer operon + + Mercury  
ter operon +   Tellurium