|
Resistance gene/Operon
|
O157 SvETEC
|
O157:K88 734/3
|
Phenotypic function/Resistance
|
Resistance observed
|
|---|
|
intI1
|
+
|
+
|
Class 1 Integron Integrase
| |
|
intI2
|
+
|
+
|
Class 2 Integron Integrase
| |
|
bla
TEM
|
+
|
+
|
Ampicillin
|
+
|
|
ampC
|
+
|
+
|
Cephalosporins
|
O157:K88 734/3 only
|
|
gyrA
|
+
|
+
|
Quinolones
|
+
|
|
aphA1
|
+
|
+
|
Aminoglycosides
|
+
|
|
APH(4)-IA
|
+
| |
Hygromycin B
|
O157 SvETEC only
|
|
strAB
|
+
|
+
|
Streptomycin
|
+
|
|
aadA
|
+
|
+
|
Streptomycin and Spectinomycin
|
+
|
|
dfrA
|
+
|
+
|
Trimethoprim
|
+
|
|
aacC
|
+
| |
Apramycin
|
O157 SvETEC only
|
|
sul1
|
+
|
+
|
Sulphonamides
|
+
|
|
sul2
|
+
|
+
|
Sulphonamides
|
+
|
|
sul3
|
+
| |
Sulphonamides
|
+
|
|
macAB
|
+
|
+
|
Macrolides
| |
|
tet operon
|
+
|
+
|
Tetracycline
|
+
|
|
cmlA
|
+
| |
Chloramphenicol
|
O157 SvETEC only
|
|
emr operon
|
+
|
+
|
RND Efflux Pump
| |
|
gadX
|
+
|
+
|
Acid Resistance Regulator
| |
|
mdt operon
|
+
|
+
|
RND Efflux Pump
| |
|
cus operon
|
+
|
+
|
Heavy Metals
| |
|
mer operon
|
+
|
+
|
Mercury
| |
|
ter operon
|
+
| |
Tellurium
| |
