Folate biosynthesis pathway reconstruction. The enzymes found in both Pediococcus damnosus LMG 28219 and Pediococcus claussenii ATCC BAA-344T are highlighted in bold, with the exception of EC 22.214.171.124 that was only found in the genome of P. claussenii ATCC BAA-344T (highlighted in bold and italic). The remaining enzymes were shared by P. damnosus LMG 28219, P. claussenii ATCC BAA-344T, and P. pentosaceus ATCC 25745. The mechanism of the reaction highlighted with a dashed arrow is uncertain and needs further investigation. The figure was constructed using the ChemBioDraw software v. 13.0 (Perkin Elmer Inc., Waltham, MA, USA). P. Pediococcus, T: type strain, ATP: adenosine triphosphate, ADP: adenosine diphosphate, AMP: adenosine monophosphate, NADP(H): nicotinamide adenine dinucleotide phosphate, pABA: 4-aminobenzoic acid, P(P)i: (pyro)phosphate, EC: enzyme commission, GTP: guanoside triphospate.