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Table 1 Functional enrichment analysis of genes encompassing the identified CNVRs

From: Copy number variations in high and low fertility breeding boars

Database PathwayName ID Statistics* Adjusted p-value
KEGG Toll-like receptor signaling pathway 04620 C = 102;O = 3;E = 0.10;R = 28.83; 0.0014
rawP = 0.0002
Fatty acid metabolism 00071 C = 43;O = 2;E = 0.04;R = 45.59; 0.0032
rawP = 0.0009
RIG-I-like receptor signaling pathway 04622 C = 71;O = 2;E = 0.07;R = 27.61; 0.0036
rawP = 0.0024
WikiPathways Fatty Acid Beta Oxidation WP143 C = 73;O = 3;E = 0.07;R = 40.28; 0.0005
rawP = 5.86e-05
Toll-like receptor signaling pathway WP75 C = 116;O = 3;E = 0.12;R = 25.35; 0.0008
rawP = 0.0002
Regulation of toll-like receptor signaling pathway WP1449 C = 154;O = 3;E = 0.16;R = 19.09; 0.0013
rawP = 0.0005
Pathway Commons Immune System 522 C = 532;O = 6;E = 0.54;R = 11.05; 0.0012
rawP = 1.62e-05
Innate Immune System 1094 C = 190;O = 4;E = 0.19;R = 20.63; 0.0012
rawP = 4.32e-05
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways 1115 C = 67;O = 3;E = 0.07;R = 43.89; 0.0012
rawP = 4.53e-05
Interferon Signaling 1123 C = 98;O = 3;E = 0.10;R = 30.00; 0.0013
rawP = 0.0001
Toll Receptor Cascades 1095 C = 90;O = 3;E = 0.09;R = 32.67; 0.0013
rawP = 0.0001
Interferon alpha/beta signaling 1122 C = 77;O = 3;E = 0.08;R = 38.19; 0.0013
rawP = 6.87e-05
Toll Like Receptor 9 (TLR9) Cascade 1084 C = 65;O = 2;E = 0.07;R = 30.16; 0.0089
rawP = 0.0020
Toll Like Receptor 2 (TLR2) Cascade 1136 C = 65;O = 2;E = 0.07;R = 30.16; 0.0089
rawP = 0.0020
TRIF mediated TLR3 signaling 1074 C = 56;O = 2;E = 0.06;R = 35.01; 0.0089
rawP = 0.0015
  1. *where C = number of reference genes in the category, O = observed number of genes in the gene set from the category, E = expected number in the category, R = Ratio of enrichment, rawP = p value from hypergeometric test, adjusted p-value = p value adjusted by the multiple test adjustment.