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Table 1 Relative changes in the yeast protein abundance when cultured in succinate versus glucose

From: Proteomic and metabolomic analysis of the carotenogenic yeast Xanthophyllomyces dendrorhous using different carbon sources

  

c Fold-change succinate/glucose

a SSP

b Assignment

L

EE

EL

S

 

Cellular Processes: Transport and Motor Proteins

    

6813

Putative coatomer subunit alpha

2.22

3.53

2.99

2.32

8703

Myosin -associated protein

26.33

2.34

3.83

2.58

8711

Myosin -associated protein

16.31

2.01

3.47

2.13

7403

KIP1 kinesin- related protein

4.68

−1.20

1.01

1.42

2503

Alpha-tubulin

3.92

−3.12

2.70

2.38

 

Environmental Information Processing and Signal Transduction

  

5515

Negative regulator of the PHO system. Ser-thr kinase

−5.15

−1.20

−2.03

−1.04

3808

Serine/threonine-protein phosphatase PP1-1

1.09

5.86

1.48

1.49

9206

Ribosomal_L15

−9.72

−10.86

−6.31

−30.40

8104

Protein PXR1

−18.08

−21.03

−22.68

−24.75

5417

Eukaryotic translation initiation factor 3 subunit H

−18.02

−1.63

2.41

−3.29

4411

Pre-mRNA-splicing factor

−49.64

−5.13

−3.64

1.09

7815

Mediator of RNA polymerase II transcription sub.14

3.62

3.10

2.24

2.05

5602

Hypothetical protein. ATP-binding, Chaperone

−5.05

1.17

−2.18

−1.25

2603

HSP60

5.25

−1.50

−1.09

−1.01

6411

Transcription factor RfeF, putative

22.00

3.95

2.84

3.20

7109

GTP-binding nuclear protein RAN

−2.19

−1.69

−1.26

−1.07

 

Metabolism

    

3715

HSP 70

1.04

2.37

1.00

1.18

7812

Vacuolar membrane ATPase subunit a precursor

2.66

2.61

4.24

1.83

8504

Glutathione S-transferase Gst3

5.43

−1.65

1.88

3.71

 

Metabolism: Lipid and Carbohydrate

   

2523

CQ798506 NID. Acetyl-CoA carboxylase, cytosolic

−4.12

−1.57

−2.23

−2.88

4603

ADR052 Wp. Simil acyl-CoA synthetase

3.96

3.75

3.98

7.02

6604

Fatty acid synthase

14.69

2.32

19.30

2.64

2319

Acetyl-CoA synthetase

−6.54

−2.51

−19.85

−1.18

6503

Citrate synthase

1.07

6.07

3.12

2.24

6609

Glucokinase

−5.48

−3.12

−4.63

−8.47

4201

Phosphoglycerate kinase

3.02

−2.30

−1.04

1.74

5314

GAPDH

11.61

−1.46

1.51

−2.33

2213

Transaldolase

1.03

−2.83

−2.42

−2.21

6610

Succinate dehydrogenase (ubiquinone)

−4.25

1.55

3.22

1.74

6403

Pyruvate dehydrogenase

−27.44

−1.20

2.54

−1.55

5509

Succinyl-CoA synthetase beta subunit

−1.15

16.26

17.02

6.02

3206

NADP+ malate dehydrogenase

36.04

1.90

38.06

3.81

4605

Pyruvate decarboxylase

5.43

3.29

3.21

2.90

4519

Glucose-6-phosphate isomerase

−5.39

−26.97

−1.06

3.10

0604

6-phosphogluconate dehydrogenase

6.28

−1.42

1.76

2.69

3331

Enolase

1.07

−3.59

−1.64

−1.75

4717

Aldehyde dehydrogenase [NAD(P)+]

4.27

2.02

−1.93

6.80

7110

Ribose-5-phosphate isomerase

1.42

−2.02

9.29

−2.32

5617

Glucose-6-P dehydrogenase

−5.94

−5.64

−10.98

−2.08

7206

Malate dehydrogenase

7.82

1.70

3.24

4.74

6516

Acyl-CoA carboxylate CoA-transferase

6.07

7.73

8.02

4.43

6109

Endo-1,3(4)-beta-glucanase -glucanase

−4.62

−1.23

−2.28

−2.36

 

Metabolism: Secondary metabolite/carotenoid biosynthesis

  

4609

Mevalonate kinase

13.23

3.51

71.38

10.07

5717

Squalene synthase

−2.19

1.28

1.01

−1.26

5303

Prenyltransferase

1.46

−1.17

−5.57

−1.11

6308

Diphosphomevalonate decarboxylase

1.62

1.25

−1.27

−1.30

3517

Phosphomevalonate kinase

1.14

4.42

1.99

2.43

7501

Astaxanthin synthase

−1.15

1.50

3.62

2.30

7311

Cytochrome P450 reductase (crtR) gene

1.62

1.40

−1.11

−2.87

 

Metabolism: Redox

    

4713

Monooxygenase

1.68

2.28

2.20

1.78

5703

Monooxygenase

2.18

3.91

1.45

2.05

5208

Alcohol dehydrogenase

−3.91

−2.74

−5.20

−8.99

5202

Dehydrogenases with different specificities SDR

3.53

1.62

1.67

1.24

7108

Mn superoxide dismutase

−27.58

−6.57

−40.12

−1.10

7105

Peroxiredoxin TSA2.

−41.82

−18.13

−57.80

−2.93

4310

Oxidoreductase

1.10

3.09

3.60

1.57

5320

Monooxygenase, putative

19.98

1.81

26.11

22.52

7618

Glutathione-disulfide reductase

33.21

3.49

1.86

1.42

2210

Short-chain dehydrogenase/reductase SDR

−10.14

−2.70

21.55

1.26

5313

Probable thioredoxin peroxidase

−8.84

1.07

−4.86

−4.04

 

Metabolism: Amino acid

    

7811

Mitochondrial isoleucyl-tRNA synthetase

1.94

2.25

−1.13

1.66

7210

RIB40 genomic DNA. Methionyl-tRNA formyltransferase

10.14

−1.18

1.78

2.03

7816

Kynurenine 3-monooxygenase

6.59

4.93

2.74

2.80

7307

Aspartate aminotransferase putative

4.58

1.60

1.03

−2.50

2628

Adenosylhomocysteinase

−27.35

1.36

−3.14

−2.53

3515

Delta-1-pyrroline-5-carboxylate dehydrogenase

−2.66

−2.32

5.77

1.93

 

Unknown

    

7715

UPF0553 protein C589.05c.

5.54

4.35

1.38

−1.51

5304

Conserved hypothetical protein

−6.74

−1.43

−2.32

−2.82

3615

YALI0F00616p

−5.60

1.39

32.23

2.13

0310

Predicted protein

3.56

−4.53

−4.39

−1.57

3002

Hypothetical protein

−2.89

−2.51

3.24

2.19

6111

Hypothetical protein

−14.03

1.15

4.27

−1.05

  1. aSSP numbers were assigned using the PDQuest software analysis. bIdentifications were obtained using the Swiss-Prot and KEGG Pathways databases and contigs of X. dendrorhous genomic DNA. cMean fold changes in succinate compared with glucose. Statistical significance was estimated by t-test (p <0.02) that is shown in italics and the Benjamini-Hochberg (p <0.05) correction shown as bold values. Abbreviations: L: lag phase, EE: Early exponential, EL: Late exponential, S: Stationary.
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BMC Genomics

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