Figure 1

Identification of differentially expressed miRNA and mRNA in kidney in rat treated with AA. A. Classification of samples according to expression intensity of the 417 detectable miRNAs. Hierarchical clustering analysis separates the 8 samples into two groups that are consistent with control and the treatment groups. Principal component analysis groups samples into the AA- treated and control clusters. B. Classification of 8 samples according to expression level of the 23939 detectable mRNAs. Hierarchical clustering analysis separates the 8 samples into two groups that are consistent with the control and treatment groups. Principal component analysis groups samples into the AA- treated and control clusters.