Figure 5

Transcripts of some ER stress sensors, chaperones, components of ERAD, and ATG8b were significantly altered in the HTorA^ΔE-expressing brains. The amount of ATF4, ATF6, calreticulin (A), ERp60, PDI, dGRP170, P58IPK (B), Hrd1, Hrd3, Derlin-1, EDEM1, EDEM2 (C) and ATG8b (D) transcripts in the HTorA^ΔE-expressing brains was significantly different from those of the HTorA^WT-expressing brains.