Figure 2From: RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in miceEffect of the number of independent biological replicates on RNA-Seq analysis. (A) DEGs were identified using a |fold change| ≥ 2.0 and P1(t) ≥ 0.8 when examining 5 independent biological replicates or a subset of 3 or 4 replicates and compared for identified genes. Correlation of gene expression fold changes and P1(t) values are illustrated comparing (B) 3 and 4, (C) 3 and 5, and (D) 4 and 5 biological replicates.Back to article page